12/7/2023 0 Comments Timi score cad risk factor![]() ![]() Presence of at least three risk factors for coronary artery disease (i.e., diabetes mellitus, hypertension, hyperlipidemia, smoking, family history).ģ. The following seven factors help assess the mortality risk:ġ. Cardiologists who performed the angiographies and echocardiographs were blinded to the TIMI scores of patients. Echocardiography study was done by an expert cardiologist at the time of admission using vivid ® S6 GE device. Stenosis of the coronary artery was given a score of 0 if narrowing was less than 50% and a score of 1 if stenosis was greater than 50%. TIMI score predictive factors (Presence of at least three risk factors for coronary artery disease, age of 65 years or older, presence of 2 or more episodes of angina 24 hours before the presentation, aspirin use in the past seven days, previous history of coronary stenosis of 50% or more, ST-segment deviations greater than or equal to 0.05 mV on initial ECG on admission, elevated serum cardiac markers of necrosis) and angiographic data were also included in the checklist.Ĭoronary artery angiography was done and reported by one expert cardiologist. Patients with unclear past medical history or past coronary angiographic history, prior coronary artery bypass graft (CABG), atypical chest pain, evidence of ST-segment elevation in the initial ECG, those who underwent the angiographic procedure due to reasons other than ischemic heart disease, and those who did not give consent for participating were excluded.ĭata on baseline characteristics, including demographics (age, sex), risk factors (weight, hypertension, diabetes, current smoking, family history of coronary artery disease), and medical history (prior angina or MI), were collected. Patients with UA or NSTEMI who underwent angiographic study were included in the study using census sampling method. Written informed consent was obtained from all the patients for participating in the study. The study was approved by the ethics committee of Shahid Beheshti University of Medical Sciences (Code: IR.1398) and the researchers adhered to the principles of the Helsinki Declaration and patient data confidentiality throughout the study. This prospective cross-sectional study was designed to evaluate the correlation between TIMI score, and the number of vessels involved in the angiographic study of NSTEMI and UA patients, presenting to Modarres Hospital, Tehran, Iran, from April 2019 to August 2020. This study aimed to evaluate the correlation between TIMI risk score and the number of vessels involved in the angiographic study of patients presenting to emergency department following UA or NSTEMI. This is particularly important for lower-middle-income countries, which are increasingly affected by cardiovascular disease epidemic and encompass different genetics and lifestyle. Hence, the development of the TIMI risk score originated from developed countries, with limited data evaluating the effectiveness in developing countries. The TIMI score was established as one of the most commonly utilized risk assessment models in the chest pain units to warrant further workup. Patients presenting with Unstable Angina (UA) or NSTEMI that fit score 3 or more on the TIMI model are mostly recommended to undergo early invasive management with cardiac angiography and revascularization if necessary ( 9). There are seven components used in the calculation of the TIMI score. The TIMI (Thrombolysis in Myocardial Infarction) research group has introduced a specific model, the TIMI risk score assessment tool, which has been found to be predictive of the severity of vascular diseases and the potential of coronary circulation involvement in chest pain patients ( 8). Nonetheless, electrocardiogram (ECG), as the most readily available diagnostic tool in chest pain units, is not adequately helpful in decision making( 7). ![]() Choosing the best treatment in the initial stages following quick diagnosis is of great importance in improving the outcome. Several randomized clinical trials performed in the past two decades have established that immediate and complete restoration of flow in the occluded artery decreases infarct size, improves survival rates, and preserves left ventricular (LV) function ( 5, 6). Each year, three million people experience ST-segment elevation MI (STEMI) and also non-ST-segment elevation MI (NSTEMI) was estimated to occur in about four million ( 4). Myocardial infarction (MI) is known as the most severe presentation of CAD and CAD accounts for 30% of all mortalities ( 3). Despite recent developments, coronary artery disease (CAD) remains the leading cause of death across the world. Advancements of cardiac care units and revascularization methods, as well as the developments in pharmacotherapy, have led to improved patient outcomes after acute coronary syndrome (ACS) ( 1, 2). ![]()
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